![]() ![]() The reports can present some differences on the basis of the surgical specimens: for example, report on transurethral resection (TUR) specimens supplies the main information that determines subsequent patient management, such as re-TUR or radical treatment, while report on cystectomy may have an effect on further adjuvant chemo/radiotherapy or appropriate surveillance. The precise description of clinical history and an adequate urological information, such as bladder lesion cystoscopic or tomographic scan appearance, timing, surgical or therapeutic procedure performed allow pathologist to decide the best approach in handling and processing the surgical specimens, so as to obtain an accurate pathology report ( 1– 5). The decision-making for the treatment of bladder cancer depends on both quality of surgical specimen and accuracy of the pathological diagnosis. In addition, critical issues encountered in the interpretation of histological samples were discussed.Ī close collaboration between urologist and pathologist is essential for accurate diagnosis and management of patient with bladder cancer. Moreover, we considered and discussed the main prognostic factors, such as histological tumor type, grade, and stage of bladder cancer, that should be described in the pathological report. We have considered handling of biopsies, transurethral resection (TUR), and cystectomy specimens to summarize the different methods of sampling and the related issues. The main (but not exclusive) research tool used was PubMed and 87 references were selected and quoted in the text. The aim of this narrative review is to provide adequate information on handling and reporting of the bladder cancer samples to improve the closely collaboration between pathologists and urologists. 2Departement of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona, Italy.1Section of Pathological Anatomy, Department of Biomedical Sciences and Public Health, Università Politecnica delle Marche, Ancona, Italy.Roberta Mazzucchelli 1 * †, Daniela Marzioni 2 †, Giovanni Tossetta 2, Laura Pepi 1 and Rodolfo Montironi 1 ![]()
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